The MLPA (Multiplex Ligation-dependent Probe Amplification) MLPA is one of the few techniques with the ability to quickly and accurately identify small deletions and duplications that may be below the resolution of FISH or aCGH. MLPA method allows to conduct a quantitative evaluation of several dozens of different nucleotide sequences of DNA within one test.
This method is used to identify:
• Autism Spectrum Disorder (SALSA MLPA KIT P343 MRC Holland) (procedure code: GEN-122A)
Regions associated with autism spectrum disorder represented in this kit:
15q11-15q13 – genes: SNRPN, UBE3A, ATP10A, GABRB3, OCA2,
16p11 – genes: LAT, SPN, MAZ, SEZ6L2, HIRIP3, DOC2A, MAPK3, CD2BP2,
22q13 – gene: SHANK3.
Tubes with blood should be sent to the Cytogenetic Laboratory of the Medical Genetics Department by expedited post, in ambient temperature, up to 48 hours from material collection.
Material: peripheral blood in EDTA tubes (1 ml blood)
Waiting time for the test result: 4 weeks
Price: 490 PLN
Detailed information available at: +48 22 3277145
The test fee can be paid directly at the Institute’s cash desk or by transfer to the following bank account: ALIOR BANK 81 2490 0005 0000 4600 8807 9430 (procedure code in the transfer title, according to the price list).
Documents:
Instructions
for taking material for testing:
download
PDF
Referral for test and declaration of informed consent: download PDF