The MLPA (Multiplex Ligation-dependent Probe Amplification)

 MLPA is one of the few techniques with the ability to quickly and accurately identify small deletions and duplications that may be below the resolution of FISH or aCGH. MLPA method allows to conduct a quantitative evaluation of several dozens of different nucleotide sequences of DNA within one test.

This method is used to identify:

• Subtelomeric aberrations (SALSA MLPA KIT P036 MRC Holland) (procedure code: GEN-104)

SALSA MLPA kit P036 Subtelomeres contains 46 MLPA probes with 2 probes for each chromosome. 41 probes are located in subtelomeric regions. For the 5 acrocentric chromosomes (13, 14, 15, 21, 22) probes are located close to the centromere. The

subtelomeric probes for the X and Y chromosome are identical as they detect sequences in the

pseudoautosomal regions (PAR1 and PAR2).

Tubes with blood should be sent to the Cytogenetic Laboratory of the Medical Genetics Department by expedited post, in ambient temperature, up to 48 hours from material collection.

Material: peripheral blood in EDTA tubes (1 ml blood)

Waiting time for the test result: 4 weeks

Price:  470 PLN

Detailed information available at: +48 22 3277145

The test fee can be paid directly at the Institute’s cash desk or by transfer to the following bank account: ALIOR BANK 81 2490 0005 0000 4600 8807 9430 (procedure code in the transfer title, according to the price list).

Documents:
Instructions for taking material for testing: download PDF

Referral for test and declaration of informed consent: download PDF